Intracellular simulated biophoton stimulation and transsynaptic signal transmission

The traditional theory holds that the information transmission between nerve cells includes electrical and chemical transmission; however, these known functional features do face some difficulties to explain fast efficient processing cognitive processes in brain due existing limitations of neuronal networks, such as dendritic axonal propagation delays well synaptic time delay have been debated for a long time. We generated three kinds ultraweak lasers, called simulated biophotons, with different spectra intensities implement intracellular stimulation single cell hippocampal areas mouse slices combined membrane potential recording biophoton imaging techniques. found can lead transsynaptic biophotonic activities ipsilateral contralateral projection circuits hippocampus. activity characteristics were related biophotons but not levels potentials before stimulation. These findings present specific neural signal transmission, which may be involved mechanisms processing, encoding, storage signals.